Supplement Foreword

Foreword Foreword

Foreword to His-bundle pacing supplement: Everything that is old will be new again.

Physiological pacing has been a term that has been used to describe many phenomena. It was used over 30 years ago to describe the advent of AV synchronous or dual chamber pacing, later the addition of the rate-responsive mode to pacing, and even more recently to describe biventricular pacing. In the last several years, there has been a resurgence of interest in pacing the conduction system: sel...

Foreword to Supplement 1: research on a polar species—the Arctic fox

The Arctic fox has a circumpolar distribution and is intensively studied because it is adapted to extreme environments and influences the ecology of many other species. We introduce here a collection of 12 articles on Arctic fox biology and management. After summarizing the main biological features of the species, we explore the peer-reviewed literature dealing with the Arctic fox through a bib...

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Editorial Foreword

Evidence is steadily accumulating that a large number of diseases in which historical therapies have made no signifi cant impact in outcome are suddenly for the fi rst time effectively treated to yield outcomes unimaginable with prior therapies. Because of the complexities of signaling mechanisms and variation in these mechanisms between disease processes, thorough and standardized testing of e...